how long does tramadol stay in your system


How Long Does Tramadol Stay in Your System?

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Tramadol is a prescription opioid used to treat medium to severe pain. It sells under the brand reputations Ultram and Conzip.

Tramadol is often for hurt after surgery. However, it may also specify chronic pain caused by cancer or neuropathy.

Tramadol can be habit-forming. In other terms, it can sometimes lead to addiction. This is achievable if you take tramadol for a long time or if it is not swallowed precisely as prescribed.

Read on to find out how this medicine works and how long it typically remains in your system.

How does it work? 

Tramadol is identical to other pain medications, such as codeine, hydrocodone, and morphine. It attaches to opioid receptors in the brainiac to block pain signals.

Tramadol has other products as well. For instance, it increases the effects of serotonin and norepinephrine, two essential chemical messengers (neurotransmitters) in the brainiac. Both play a role in pain perception.

The goal of pain relief is to help you work better in your day-to-day life. But, unfortunately, pain medicines, like tramadol, don’t fix what’s driving your pain. Often, they don’t take the pain away entirely, either.

Does it come in different forms and strengths? 

Yes. Tramadol is known in different forms, including tablets and capsules. Outside the United States, it’s also unrestricted as drops or injections.

Tramadol injection drops and some kinds of tablets and capsules are fast-acting. They start operating in 30 to 60 minutes. However, their products wear off within 4 to 6 hours.

Fast-acting tramadol comes in doses of 50 to 100 milligrams (mg). It is usually defined as short-term (acute) pain.

Time-release or slow-acting conditions of tramadol include pills and capsules. They take an extended time to start operating, but their effects last 12 or 24 hours. During that time, tramadol is released slowly.

Time-release tramadol comes in amounts between 100 and 300 mg. This type is more likely to be long-term (chronic) pain.

How long does it last in your system? 

Tramadol stays in your saliva, blood, urine, and hair for various lengths. Some of these are the same for other opioid drugs and are not specific to tramadol.

Detection timeframes

  • Saliva: Tramadol is noticeable in saliva for up to 48 hours after it’s taken.
  • Blood: Tramadol is evident in blood for up to 48 hours after it’s taken.
  • Urine: Tramadol is observable in urine for 24 to 72 hours after it’s taken.
  • Hair: Tramadol is discernible in hair for 30 to 90 days. Trusted Source after it’s taken.

Remember that most necessary drug tests, including 5- and 10-panel tests, do not screen for tramadol. However, ordering a particular difficulty for prescription pain drugs, including tramadol, is possible.

What can impact how long it remains in your body?

Many different factors can influence how long tramadol stays in your body. These include:

  • How much do you take (dosage)? The more increased the dose, the more extended tramadol will stay in your system.
  • How often do you take tramadol? Generally, a single dose will remain in your system for the briefest time. Taking more than one dose or taking tramadol regularly stays in your procedure for a more extended period.
  • How you took it (route of administration). In general, tramadol drops or injections are interesting and excreted faster than pill forms of medication.
  • Your metabolism. Metabolism is the chemical method of breaking down substances you ingest, such as food or medicine. Your metabolic rate can affect many things, including your training level, age, diet, body document, and genetics. Slow metabolism may increase the time it brings to break down tramadol.
  • Your organ function. Smaller kidney or liver function can increase the time it takes for your body to get freed of tramadol.
  • Your age. If you’re over 75, it may take your body to elongate to get rid of tramadol.

Safety issues

Tramadol arrives with a risk of mild to severe side outcomes.

The risk of side effects rises according to how much you take. So if you take more than specified, you also increase your risk of side impacts.

More common side impacts of tramadol contain:

  • constipation
  • depressed spirit
  • dizziness
  • sedation or exhaustion
  • waterless mouth
  • headache
  • crankiness
  • itching
  • nausea or vomiting
  • sweating
  • weakness

Other side effects are less common but may be severe. They can enclose:

  • slowed breathing
  • adrenal deficiency
  • low grades of androgen (male) hormones
  • seizures
  • serotonin syndrome
  • suicidal ideas
  • overdose

Tramadol use comes with other risks. These include:

Addiction and withdrawal. Tramadol is habit-forming, which suggests that you can become conditional on it. If this happens and you stop taking it, you might experience withdrawal symptoms. You can evade this by gradually decreasing your dose. If you’re nervous about tramadol dependence, talk to your doctor.

Drug relations. Tramadol may interact with other medicines you’re taking. This can reduce tramadol’s energy and, in some cases, cause serious side effects. It would benefit if you didn’t drink alcohol or use certain drugs while taking tramadol. Make sure your doctor knows what you’re taking.

Life-threatening consequences for children and pets. Tramadol is processed differently by kids, dogs, and cats. So if you’re taking tramadol, keep it safe and secure. A child or pet ingests tramadol can cause serious side effects, including death.

Life-threatening effects for growing fetuses. If you’re pregnant, taking tramadol can hurt your baby. Let your doctor know instantly if you are or believe you might be pregnant. Tramadol can also contact your baby through your breast milk. So avoid breastfeeding while taking tramadol.

Impairment. Tramadol can damage your memory. It can also influence the way you process visual and spatial details. Avoid moving or operating machinery while bringing tramadol.

If you’re taking tramadol, it’s essential to take the time to read the warnings on the label and to talk to your doctor or druggist if you have any concerns or questions.

The bottom line

Tramadol is a synthetic opioid often named for pain after surgery and other regular pain conditions.

Tramadol can stay in your plan for up to 72 hours. However, the portion of time it takes to exit your procedure can be affected by many other factors, such as the dosage, the way you took it, and even your metabolism.

To reduce the risk of addiction, taking only tramadol for a short time and precisely as required is essential. Besides the risk of dependence, there are other side effects such as constipation, fatigue, changes in mood, and nausea.

It’s important to talk to your physician or pharmacist if you have any questions or concerns about tramadol.


  1. Drug Enforcement Administration. (2018). Tramadol.
  2. National Institute on Medicine Abuse. (2018). Prescription Opioids.
  3. World Health Organization. (2014). Tramadol: Update Review Report.
  4. The University of Wisconsin Health. (2018). Tramadol.
  5. DrugBank. Tramadol.
  6. Arup Laboratories. (2019). Drug Plasma Half-Life and Urine Detection Window.
  7. U.S. Department of Health and Human Services. (2010). Drug Testing in Child Welfare: Practice and Policy Considerations.
  8. Hadidi, K., Almasad, J., Al-Nsour, T., Abu-Ragheib, S. (2003). Determination of tramadol in hair using solid phase extraction and GC-MSForensic Science International, 135, 129-136.
  9. Substance Abuse and Mental Health Services Administration. (2018). Critical Substance Abuse and Mental Health Indicators in the United States: Results from the 2017 National Survey on Drug Use and Health.
  10. Meals and Drug Administration. (2009). Ultram.
  11. American Psychiatric Association. (2013). Diagnostic and statistical manual of cognitive disorders (5th ed.). Arlington, VA: American Psychiatric Publishing.
  12. National Institute on Drug Misuse. (2019). Treatment Approaches for Drug Addiction.


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